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Article

Role of RANK and Akt1 activation in human osteosarcoma progression: A clinicopathological study

19 Apr 2017

Abstract excerpt

The receptor activator of nuclear factor κB (RANK) axis is the fundamental signaling pathway in bone formation as well as bone tumor pathophysiology. The aim of the present study was to evaluate the impact of the expression of RANK and its downstream signaling molecule Akt1 on tumor progression in patients with osteosarcoma. Expression of RANK and Akt1 was examined in 78 human osteosarcoma samples by...

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PMID: 28587351
DOI: 10.3892/etm.2017.4360

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