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Article

Insight Into the Function of RIPK4 in Keratinocyte Differentiation and Carcinogenesis

14 Aug 2020

Abstract excerpt

The receptor-interacting protein kinase 4 (RIPK4), a member of the RIPK family, was originally described as an interaction partner of protein kinase C (PKC) β and PKCδ. RIPK4 is identified as a key regulator of keratinocyte differentiation, cutaneous inflammation, and cutaneous wound repair. The mechanism by which RIPK4 integrates upstream signals to initiate specific responses remains elusive. Previous studies...

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PMID: 32923402
DOI: 10.3389/fonc.2020.01562

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