TTN genotype is associated with fascicle length and marathon running performance.

doi:10.1111/sms.12927

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Article

TTN genotype is associated with fascicle length and marathon running performance.

Scandinavian journal of medicine & science in sports - 1 Feb 2018

Stebbings G K, Williams A G, Herbert A J, Lockey S J, Heffernan S M, Erskine R M, Morse C I, Day S H

Abstract excerpt

Titin provides a molecular blueprint for muscle sarcomere assembly, and sarcomere length can vary according to titin isoform expression. If variations in sarcomere length influence muscle fascicle length, this may provide an advantage for running performance. Thus, the aim of this study was to investigate whether the titin (TTN) rs10497520 polymorphism was associated with muscle fascicle length in recreationally...

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PMID: 28581678
DOI: 10.1111/sms.12927

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