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Article

MSTN genotype (g.66493737C/T) association with speed indices in Thoroughbred racehorses.

Journal of applied physiology (Bethesda, Md. : 1985) - 1 Jan 2012

Hill Emmeline W, Fonseca Rita G, McGivney Beatrice A, Gu Jingjing, MacHugh David E, Katz Lisa M

Abstract excerpt

Sequence variation at the equine myostatin gene (MSTN) locus has previously been shown to have a singular genomic influence on optimum race distance in Thoroughbred racehorses. Myostatin, encoded by the MSTN gene, is a member of the TGF-β superfamily that regulates skeletal muscle development in a range of mammalian species including the horse. In the Thoroughbred, the C-allele at the g.66493737C/T SNP has been...

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PMID: 22016373
DOI: 10.1152/japplphysiol.00793.2011

Genes

MSTN

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