Article
TTN Variants Are Associated with Physical Performance and Provide Potential Markers for Sport-Related Phenotypes.
International journal of environmental research and public health - 17 Aug 2022
Leońska-Duniec Agata, Borczyk Małgorzata, Piechota Marcin, Korostyński Michał, Brodkiewicz Andrzej, Cięszczyk Paweł
Abstract excerpt
TTN encodes the third myofilament, titin, which plays structural, mechanical, regulatory, and developmental roles in sarcomeres. The aim of this research was to determine the interaction between novel and previously described TTN variants and athletic performance, as well as competition level, in Caucasians. Firstly, 100 athletes and 47 controls were recruited, and whole-genome sequencing was performed. Secondly,...
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