Article
A Potential Role of Esophageal Cancer Related Gene-4 for Atrial Fibrillation.
Scientific reports - 2 Jun 2017
Huang Li, Yu Hua, Fan Xinrong, Li Xue, Mao Liang, Cheng Jun, Zeng Xiaorong, Dang Xitong
Abstract excerpt
Epidemiological studies have shown a strong correlation between tumor and AF. However, the molecular link between tumor and AF remains unknown. ECRG4, a tumor suppressor gene that is expressed in the A-V node and in sporadic ventricular myocytes, inhibits tumorigenesis and monitors tissue homeostasis by functioning as a 'sentinel' molecule gauging inflammatory and cell proliferative responses. To explore the...
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