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Article

MicroRNA-328 Contributes to Adverse Electrical Remodeling in Atrial Fibrillation

23 Nov 2010

Abstract excerpt

BACKGROUND: A characteristic of both clinical and experimental atrial fibrillation (AF) is atrial electric remodeling associated with profound reduction of L-type Ca(2+) current and shortening of the action potential duration. The possibility that microRNAs (miRNAs) may be involved in this process has not been tested. Accordingly, we assessed the potential role of miRNAs in regulating experimental AF. METHODS AND...

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Share to Atrial Fibrillation Management and Outcomes
Share to Cardiac electrophysiology and arrhythmias
Share to MicroRNA in disease regulation

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PMID: 21098446
DOI: 10.1161/circulationaha.110.958967

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