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Article

Distinct roles for the mTOR pathway in postnatal morphogenesis, maturation and function of pancreatic islets.

Development (Cambridge, England) - 1 Jul 2017

Sinagoga Katie L, Stone William J, Schiesser Jacqueline V, Schweitzer Jamie I, Sampson Leesa, Zheng Yi, Wells James M

Abstract excerpt

While much is known about the molecular pathways that regulate embryonic development and adult homeostasis of the endocrine pancreas, little is known about what regulates early postnatal development and maturation of islets. Given that birth marks the first exposure to enteral nutrition, we investigated how nutrient-regulated signaling pathways influence postnatal islet development in mice. We performed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28576773
DOI: 10.1242/dev.146316
PMCID: PMC5536865

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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