Article
Analysis of cytokine genes polymorphism as markers for inhibitor development in haemophilia A.
International journal of immunogenetics - 1 Apr 2010
Chaves D, Belisário A, Castro G, Santoro M, Rodrigues C
Abstract excerpt
Antibodies that block factor VIII (FVIII) activity appear in some haemophilia A patients treated with FVIII replacement therapy and severely impaired treatment. To date, the mechanisms that lead to this immune response are unknown. In this work, haplotypes of cytokine interleukin 10 (IL-10) gene...
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