Article
Dilated cardiomyopathy-induced disruption of basement membrane alters the lever systems acting on the heart.
Medical hypotheses - 1 Jun 2017
Mohamed Iman A, El-Badri Nagwa, Zaher Amr
Abstract excerpt
Dilated cardiomyopathy (DCM) is considered the most common form of non-ischemic heart diseases. DCM, occurs in response to both non-genetic and genetic factors, and has been associated with cytoskeletal protein mutations, impairing the contractile apparatus of cardiac myocytes. However, the pathology underlying the marked left ventricular dilatation remains unclear. Moreover, patients with end-stage DCM show...
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