Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Vinculin and Talin: Focus on the Myocardium

1 Dec 2009

Abstract excerpt

Cardiomyopathy is a heart muscle disease caused by decreased contractility of the ventricles leading to heart failure and premature death. Multiple conditions like ischemic heart disease (atherosclerosis), hypertension, diabetes, viral infection, alcohol abuse, obesity and genetic mutations can lead to cardiomyopathy. Single gene mutations in sarcomeric proteins, Z-disk-associated proteins, membrane/associated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cardiomyopathy and Myosin Studies
Share to Cardiovascular Effects of Exercise
Share to Muscle Physiology and Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19952892
DOI: 10.2310/jim.0b013e3181c5e074

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Vinculin and Talin: Focus on the MyocardiumPMID 19952892Read ↗

Heterozygous inactivation of the vinculin gene predisposes to stress-induced cardiomyopathy.Semantic proximity Read ↗

Dilated Cardiomyopathy Associated With Deficiency of the Cytoskeletal Protein MetavinculinSemantic proximity Read ↗

Thin filament cardiomyopathies: A review of genetics, disease mechanisms, and emerging therapeuticsSemantic proximity Read ↗

Cardiac Troponin and Tropomyosin: Structural and Cellular Perspectives to Unveil the Hypertrophic Cardiomyopathy PhenotypeSemantic proximity Read ↗

Understanding the molecular basis of cardiomyopathy.Semantic proximity Read ↗

New Insights in RBM20 Cardiomyopathy.Semantic proximity Read ↗

Cardiac titin and heart disease.Semantic proximity Read ↗

Vinculin network-mediated cytoskeletal remodeling regulates contractile function in the aging heart.Semantic proximity Read ↗

Identification of a metavinculin missense mutation, R975W, associated with both hypertrophic and dilated cardiomyopathy.Semantic proximity Read ↗

The Sarcomeric Spring Protein Titin: Biophysical Properties, Molecular Mechanisms, and Genetic Mutations Associated with Heart Failure and Cardiomyopathy.Semantic proximity Read ↗

Establishment of a human iPSC (ZZUNEUi026-A) from a dilated cardiomyopathy patient carrying heterozygous Vinculin (c. 625A > T) mutant.Semantic proximity Read ↗

[The cytoskeleton and related proteins mutation in the myocardium].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.