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Article

A disease-linked ULBP6 polymorphism inhibits NKG2D-mediated target cell killing by enhancing the stability of NKG2D ligand binding

30 May 2017

Abstract excerpt

polymorphisms affect the strength of human lymphocyte responses to cellular stress signals and may offer opportunities for therapeutic intervention.

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Identifiers

PMID: 28559451
DOI: 10.1126/scisignal.aai8904

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A disease-linked ULBP6 polymorphism inhibits NKG2D-mediated target cell killing by enhancing the stability of NKG2D ligand bindingPMID 28559451Read ↗

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Characterisation of RAET1E/ULBP4 exon 4 and 3' untranslated region genetic architecture reveals further diversity and allelic polymorphism.Semantic proximity Read ↗

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A forward genetic screen reveals novel independent regulators of ULBP1, an activating ligand for natural killer cellsSemantic proximity Read ↗

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