Article
CD36 gene is associated with intraocular pressure elevation after intravitreal application of anti-VEGF agents in patients with age-related macular degeneration: Implications for the safety of the therapy.
Ophthalmic genetics - 1 Jan 2000
Matušková Veronika, Balcar Vladimir J, Khan Naim A, Bonczek Ondřej, Ewerlingová Laura, Zeman Tomáš, Kolář Petr, Vysloužilová Daniela, Vlková Eva, Šerý Omar
Abstract excerpt
BACKGROUND: The wet form of age-related macular degeneration (AMD) is characterized by pathological vascularization of the outer retinal layers. The condition responds to treatment with antibodies against vascular endothelial growth factor (VEGF), but the patients receiving such anti-VEGF therapy sometimes show undesirable acute short-term increases in the intraocular pressure (IOP). The cause of this adverse...
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