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Article

Predictive value of VEGF A and VEGFR2 polymorphisms in the response to intravitreal ranibizumab treatment for wet AMD.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie - 1 Mar 2014

Cruz-Gonzalez Fernando, Cabrillo-Estévez Lucía, López-Valverde Gloria, Cieza-Borrella Clara, Hernández-Galilea Emiliano, González-Sarmiento Rogelio

Abstract excerpt

BACKGROUND: To determine whether gene polymorphisms of the vascular endothelial growth factor A (VEGF A) and its receptor (VEGFR) influence the response to a variable-dosing treatment regimen with ranibizumab for age-related macular degeneration. METHODS: This prospective cohort study included 94 patients (94 eyes) with exudative age-related macular degeneration (AMD) treated with ranibizumab. Patients underwent...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 24522370
DOI: 10.1007/s00417-014-2585-7

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Predictive value of VEGF A and VEGFR2 polymorphisms in the response to intravitreal ranibizumab treatment for wet AMD.PMID 24522370Read ↗

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