Article
Genetic susceptibility to cardiovascular disease and risk of dementia.
Translational psychiatry - 30 May 2017
Karlsson I K, Ploner A, Song C, Gatz M, Pedersen N L, Hägg S
Abstract excerpt
Several studies have shown cardiovascular disease (CVD) to be associated with dementia, but it is not clear whether CVD per se increases the risk of dementia or whether the association is due to shared risk factors. We tested how a genetic risk score (GRS) for coronary artery disease (CAD) affects dementia risk after CVD in 13 231 Swedish twins. We also utilized summarized genome-wide association data to study...
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