Heritability and linkage analysis of personality in bipolar disorder.

doi:10.1016/j.jad.2013.06.015

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Article

Heritability and linkage analysis of personality in bipolar disorder.

Journal of affective disorders - 1 Nov 2013

Greenwood Tiffany A, Badner Judith A, Byerley William, Keck Paul E, McElroy Susan L, Remick Ronald A, Dessa Sadovnick A, Kelsoe John R

Abstract excerpt

BACKGROUND: The many attempts that have been made to identify genes for bipolar disorder (BD) have met with limited success, which may reflect an inadequacy of diagnosis as an informative and biologically relevant phenotype for genetic studies. Here we have explored aspects of personality as quantitative phenotypes for bipolar disorder through the use of the Temperament and Character Inventory (TCI), which...

Topics

Adult
Bipolar Disorder
Depressive Disorder, Major
Endophenotypes
Family
Female
Genetic Linkage
Genetic Predisposition to Disease
Genome-Wide Association Study
Genotype
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Middle Aged

Personality

Personality Inventory

Polymorphism, Single Nucleotide

Temperament

Source

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Identifiers

PMID: 23972719
DOI: 10.1016/j.jad.2013.06.015
PMCID: PMC3797235

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