Article
Intrahepatic HCV RNA Level and Genotype 1 Independently Associate with Hepatic Reticulon 3 Expression.
Anticancer research - 1 Jun 2017
Lin Chih-Lang, Chien Rong-Nan, Liang Kung-Hao, Ke Po-Yuan, Huang Ya-Hui, Yeh Chau-Ting
Abstract excerpt
Background /Aim: Reticulon 3 (RTN3), resides predominantly in the endoplasmic reticulum and has opposite regulatory effects on Hepatitis C virus (HCV) replication through interacting with NS5A and NS4B proteins. This study aimed to unravel the actual effect of RTN3 on HCV replication. MATERIALS AND METHODS: A total of 115 HCV-related hepatocellular carcinoma patients receiving hepatectomy was enrolled in this...
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