Article
Reticulon-3 modulates the incorporation of replication competent hepatitis C virus molecules for release inside infectious exosomes
17 Sept 2020
Abstract excerpt
BACKGROUND: Cell released microvesicles specifically, exosomes, play an important role in mediating immunologic escape, treatment resistance, and disease persistence of Hepatitis C virus (HCV) infection. Reports on the molecular compositions of exosomes released by cells under diverse conditions, especially during viral infections, suggest that their cargo contents are not randomly loaded. However, the precise...
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