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CD44 Splice Variants as Potential Players in Alzheimer’s Disease Pathology

25 May 2017

Abstract excerpt

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive deficits, deposition of amyloid-β (Aβ) plaques, intracellular neurofibrillary tangles, and neuronal cell death. Neuroinflammation is commonly believed to participate in AD pathogenesis. CD44 is an inflammation-related gene encoding a widely-distributed family of alternatively spliced cell surface glycoproteins that...

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PMID: 28550248
DOI: 10.3233/jad-161245

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