Article
Deep sequencing of atrial fibrillation patients with mitral valve regurgitation shows no evidence of mosaicism but reveals novel rare germline variants.
Heart rhythm - 1 Oct 2017
Gregers Emilie, Ahlberg Gustav, Christensen Thea, Jabbari Javad, Larsen Kirstine O, Herfelt Cecilie B, Henningsen Kristoffer M, Andreasen Laura, Thiis Jens J, Lund Jens, Holme Susanne, Haunsø Stig, Bentzen Bo H, Schmitt Nicole, Svendsen Jesper H, Olesen Morten S
Abstract excerpt
BACKGROUND: Atrial fibrillation (AF) is the most common cardiac arrhythmia. Valvular heart disease is a strong predictor, yet the underlying molecular mechanisms are unknown. OBJECTIVE: The purpose of this study was to investigate the prevalence of somatic variants in AF candidate genes in an AF patient population undergoing surgery for mitral valve regurgitation (MVR) to determine whether these patients are...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.