Article
Relationship between IFNA1, IFNA5, IFNA10, and IFNA17 gene polymorphisms and Crimean-Congo hemorrhagic fever prognosis in a Turkish population range.
Journal of medical virology - 1 Jul 2016
Elaldi Nazif, Yilmaz Meral, Bagci Binnur, Yelkovan Izzet, Bagci Gokhan, Gozel Mustafa Gokhan, Engin Aynur, Bakir Mehmet, Dokmetas Ilyas
Abstract excerpt
Crimean-Congo hemorrhagic fever (CCHF) is a fatal emerging acute viral infection. Not much is known regarding the pathogenic mechanisms and the reasons behind severe or mild disease courses in CCHF. IFN-alpha (IFNA) is one of the essential cytokines in the immune system. Existence of single nucleotide gene polymorphisms (SNPs) in cytokines can cause susceptibility or resistance to viral agents and different...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
