Article
Common variants upstream of MLF1 at 3q25 and within CPZ at 4p16 associated with neuroblastoma.
PLoS genetics - 1 May 2017
McDaniel Lee D, Conkrite Karina L, Chang Xiao, Capasso Mario, Vaksman Zalman, Oldridge Derek A, Zachariou Anna, Horn Millicent, Diamond Maura, Hou Cuiping, Iolascon Achille, Hakonarson Hakon, Rahman Nazneen, Devoto Marcella, Diskin Sharon J
Abstract excerpt
Neuroblastoma is a cancer of the developing sympathetic nervous system that most commonly presents in young children and accounts for approximately 12% of pediatric oncology deaths. Here, we report on a genome-wide association study (GWAS) in a discovery cohort or 2,101 cases and 4,202 controls of European ancestry. We identify two new association signals at 3q25 and 4p16 that replicated robustly in multiple...
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