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Article

Fixed differences in the 3'UTR of buffalo PRNP gene provide binding sites for miRNAs post-transcriptional regulation.

Oncotarget - 11 Jul 2017

Zhao Hui, Wang Siqi, Guo Lixia, Du Yanli, Liu Linlin, Ma Tengfei, Otecko Newton O, Li Canpeng, Zhang Yaping

Abstract excerpt

Bovine spongiform encephalopathy, a member of transmissible spongiform encephalopathies, has not been reported in buffaloes, Bubalus bubalis. Prion protein (PrP), encoded by the prion protein gene (PRNP), is fundamental in the pathogenesis of transmissible spongiform encephalopathies. We previously showed that buffaloes express more PrP proteins but lower PRNP mRNA than cattle in several pivotal tissues like the...

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Identifiers

PMID: 28545018
DOI: 10.18632/oncotarget.17545
PMCID: PMC5542244

Genes

PRNP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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