Article
MicroRNA sequence variation can impact interactions with target mRNA in cattle.
Gene - 5 Jun 2023
Hao Dan, Wang Xiao, Yang Yu, Chen Hong, Thomsen Bo, Holm Lars-Erik
Abstract excerpt
BACKGROUND: Small non-coding microRNAs (miRNAs) are important modulators at post-transcriptional levels. Single-nucleotide polymorphisms (SNPs) located in miRNA genes can alter the secondary structure of pre-miRNA to either impair or promote the miRNA maturation processes. Furthermore, SNPs located in the miRNA seed regions can stabilize or disturb miRNA-target interactions, thereby, quantitatively influence the...
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