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Article

Prognostic significance of promoter CpG island methylation of obesity‐related genes in patients with nonmetastatic renal cell carcinoma

23 May 2017

Abstract excerpt

BACKGROUND Greater than 40% of renal cell carcinoma (RCC) cases in the United States are attributed to excessive body weight. Moreover, obesity also may be linked to RCC prognosis. However, the molecular mechanisms underlying these associations are unclear. In the current study, the authors evaluated the role of promoter methylation in obesity‐related genes in RCC tumorigenesis and disease recurrence. METHODS...

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Share to Epigenetics and DNA Methylation
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PMID: 28543182
DOI: 10.1002/cncr.30707

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