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Article

An epidemiologic and genomic investigation into the obesity paradox in renal cell carcinoma.

Journal of the National Cancer Institute - 18 Dec 2013

Hakimi A Ari, Furberg Helena, Zabor Emily C, Jacobsen Anders, Schultz Nikolaus, Ciriello Giovanni, Mikklineni Nina, Fiegoli Brandon, Kim Philip H, Voss Martin H, Shen Hui, Laird Peter W, Sander Chris, Reuter Victor E, Motzer Robert J, Hsieh James J, Russo Paul

Abstract excerpt

BACKGROUND: Obesity increases risk for clear-cell renal cell carcinoma (ccRCC), yet obese patients appear to experience longer survival than nonobese patients. We examined body mass index (BMI) in relation to stage, grade, and cancer-specific mortality (CSM) while considering detection bias, nutritional status, and molecular tumor features. METHODS: Data were available from 2119 ccRCC patients who underwent renal...

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Identifiers

PMID: 24285872
DOI: 10.1093/jnci/djt310
PMCID: PMC3866155

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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