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Article

Potential Susceptibility Loci Identified for Renal Cell Carcinoma by Targeting Obesity-Related Genes.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Sept 2017

Shu Xiang, Purdue Mark P, Ye Yuanqing, Tu Huakang, Wood Christopher G, Tannir Nizar M, Wang Zhaoming, Albanes Demetrius, Gapstur Susan M, Stevens Victoria L, Rothman Nathaniel, Chanock Stephen J, Wu Xifeng

Abstract excerpt

Background: Obesity is an established risk factor for renal cell carcinoma (RCC). Although genome-wide association studies (GWAS) of RCC have identified several susceptibility loci, additional variants might be missed due to the highly conservative selection.Methods: We conducted a multiphase study utilizing three independent genome-wide scans at MD Anderson Cancer Center (MDA RCC GWAS and MDA RCC OncoArray) and...

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Source

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Identifiers

PMID: 28626070
DOI: 10.1158/1055-9965.EPI-17-0141
PMCID: PMC5581698

Genes

PLIN2
SMAD3
TSC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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