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Article

Promiscuous signaling by a regulatory system unique to the pandemic PMEN1 pneumococcal lineage.

PLoS pathogens - 1 May 2017

Kadam Anagha, Eutsey Rory A, Rosch Jason, Miao Xinyu, Longwell Mark, Xu Wenjie, Woolford Carol A, Hillman Todd, Motib Anfal Shakir, Yesilkaya Hasan, Mitchell Aaron P, Hiller N Luisa

Abstract excerpt

Streptococcus pneumoniae (pneumococcus) is a leading cause of death and disease in children and elderly. Genetic variability among isolates from this species is high. These differences, often the product of gene loss or gene acquisition via horizontal gene transfer, can endow strains with new molecular pathways, diverse phenotypes, and ecological advantages. PMEN1 is a widespread and multidrug-resistant...

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Share to Bacterial Adhesion
Share to Gene Expression Regulation, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Transfer, Horizontal

Share to Nasopharynx

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Source

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Identifiers

PMID: 28542565
DOI: 10.1371/journal.ppat.1006339
PMCID: PMC5436883

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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