Article
PPARD is an Inhibitor of Cartilage Growth in External Ears.
International journal of biological sciences - 1 Jan 2017
Zhang Zhen, Duan Yanyu, Wu Zhongping, Zhang Hui, Ren Jun, Huang Lusheng
Abstract excerpt
Peroxisome proliferator-activated receptor beta/delta (PPARD) is an important determinant of multiple biological processes. Our previous studies identified a missense mutation in the PPARD gene that significantly reduces its transcription activity, and consequently causes enlarged external ears in pigs. However, the mechanisms underlying the causality has remained largely unknown. Here, we show that PPARD retards...
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