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Article

A Genetic Variant in FIGN Gene Reduces the Risk of Congenital Heart Disease in Han Chinese Populations.

Pediatric cardiology - 1 Aug 2017

Wang Dan, Chu Maoping, Wang Feng, Zhou Aihua, Ruan Miaohua, Chen Yiming

Abstract excerpt

Congenital heart disease (CHD) is one of the most common birth anomalies worldwide. Folate deficiency is an independent risk factor for CHD. Genome-wide association studies (GWAS) revealed that human folate level could be significantly influenced by fidgetin (FIGN), methylenetetrahydrofolate reductase (MTHFR), prickle homolog 2 (PRICKLE2), synaptotagmin 9 (SYT9), gamma-aminobutyric acid B receptor 2 (GABBR2), and...

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Source

Identifiers

PMID: 28534241
DOI: 10.1007/s00246-017-1636-3

Genes

FIGN
ALPL
GABBR2
MTHFR
PRICKLE2
SYT9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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