Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Methylparaben and butylparaben alter multipotent mesenchymal stem cell fates towards adipocyte lineage.

Toxicology and applied pharmacology - 15 Aug 2017

Hu Pan, Overby Haley, Heal Emily, Wang Shu, Chen Jiangang, Shen Chwan-Li, Zhao Ling

Abstract excerpt

Paraben esters and their salts are widely used as preservatives in cosmetics, personal care products, pharmaceuticals, and foods. We previously reported that parabens promoted adipocyte differentiation in vitro and increased adiposity but suppressed serum marker of bone formation in vivo. Here, we investigated the effects of parabens (methylparaben and butylparaben) on modulating cell fate of multipotent stem...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipocytes
Share to Adipogenesis
Share to Chondrogenesis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mesenchymal Stem Cells

Share to Mice, Inbred C3H

Share to Osteogenesis

Share to PPAR gamma

Share to Receptors, Glucocorticoid

Source

Open in PubMed Open full text

Identifiers

PMID: 28527915
DOI: 10.1016/j.taap.2017.05.019
PMCID: PMC5528845

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Methylparaben and butylparaben alter multipotent mesenchymal stem cell fates towards adipocyte lineage.PMID 28527915Read ↗

Structurally-diverse, PPARγ-activating environmental toxicants induce adipogenesis and suppress osteogenesis in bone marrow mesenchymal stromal cells.Semantic proximity Read ↗

2,4-Di-tert-butylphenol Induces Adipogenesis in Human Mesenchymal Stem Cells by Activating Retinoid X ReceptorsSemantic proximity Read ↗

Exploring the Impact of Propylparaben on Trophoblast Function: A Comprehensive In Vitro Study of Toxicity and Gene ExpressionSemantic proximity Read ↗

Worsening Effect of Bisphenols Toxicity and Organ Vulnerability<strong> </strong>Semantic proximity Read ↗

Mesenchymal Stromal Cells showed an alteration of differentiation potential under Environmental Micro and Nanoplastics ExposureSemantic proximity Read ↗

A mixture of endocrine disrupting chemicals linked to lower birth weight induces adipogenesis and transcriptional changes related to birth weight alterations and diabetesSemantic proximity Read ↗

Parabens Promote Pro-Tumorigenic Effects in Luminal Breast Cancer Cell Lines with Diverse Genetic AncestrySemantic proximity Read ↗

A Data-Driven Transcriptional Taxonomy of Adipogenic Chemicals to Identify White and Brite AdipogensSemantic proximity Read ↗

Tributyltin induces a transcriptional response without a brite adipocyte signature in adipocyte modelsSemantic proximity Read ↗

Developmental toxicity and skin sensitization potential of synthetic phenolic antioxidants and butylated hydroxytoluene transformation products: Insights from human embryonic stem cell modelsSemantic proximity Read ↗

The Organophosphate Esters Used as Flame Retardants and Plasticizers Affect H295R Adrenal Cell Phenotypes and Functions.Semantic proximity Read ↗

Adverse outcomes of the newly emerging bisphenol A substitutesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.