Article
Copy number alterations in prostate tumors and disease aggressiveness.
Genes, chromosomes & cancer - 1 Jan 2012
Cheng Iona, Levin Albert M, Tai Yu Chuan, Plummer Sarah, Chen Gary K, Neslund-Dudas Christine, Casey Graham, Rybicki Benjamin A, Witte John S
Abstract excerpt
Detecting genomic alterations that result in more aggressive prostate cancer may improve clinical treatment and our understanding of the biology underlying this common but complex disease. To this end, we undertook a genome-wide copy number alterations (CNAs) study of clinicopathological characteristics of 62 prostate tumors using the Illumina 1M single nucleotide polymorphism array. The highest overall...
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