Article
Genome-wide genotyping in Parkinson's disease and neurologically normal controls: first stage analysis and public release of data.
The Lancet. Neurology - 1 Nov 2006
Fung Hon-Chung, Scholz Sonja, Matarin Mar, Simón-Sánchez Javier, Hernandez Dena, Britton Angela, Gibbs J Raphael, Langefeld Carl, Stiegert Matt L, Schymick Jennifer, Okun Michael S, Mandel Ronald J, Fernandez Hubert H, Foote Kelly D, Rodríguez Ramón L, Peckham Elizabeth, De Vrieze Fabienne Wavrant, Gwinn-Hardy Katrina, Hardy John A, Singleton Andrew
Abstract excerpt
BACKGROUND: Several genes underlying rare monogenic forms of Parkinson's disease have been identified over the past decade. Despite evidence for a role for genetics in sporadic Parkinson's disease, few common genetic variants have been unequivocally linked to this disorder. We sought to identify any common genetic variability exerting a large effect in risk for Parkinson's disease in a population cohort and to...
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