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Article

Mitochondrial DNA heteroplasmy in cardiac tissue from individuals with and without coronary artery disease.

Mitochondrial DNA. Part A, DNA mapping, sequencing, and analysis - 1 May 2018

Hefti Erik, Blanco Javier Guillermo

Abstract excerpt

The cellular environment associated with coronary artery disease (CAD) can lead to mitochondrial DNA (mtDNA) damage. Mitochondrial variants in some copies of mtDNA (heteroplasmy) and mtDNA content are potential genetic biomarkers for CAD-associated disease states. Massively parallel sequencing and qRT-PCR techniques were used to measure heteroplasmic variants and mtDNA content in heart samples from donors with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 28521548
DOI: 10.1080/24701394.2017.1325480
PMCID: PMC5694712

Genes

CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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