MiR‐2392 suppresses metastasis and epithelial–mesenchymal transition by targeting MAML3 and WHSC1 in gastric cancer

Abstract excerpt

ABSTRACT MicroRNAs have emerged as essential regulators of various cellular processes. We identified the role and underlying mechanisms of miR‐2392 in gastric cancer (GC) metastasis. MiR‐2392 was down‐regulated in GC cell lines and tissues, and overexpression of miR‐2392 significantly inhibited GC invasion and metastasis in vitro and in vivo. We identified MAML3 and WHSC1 as novel targets of miR‐2392, and...

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