Article
The Mycobacterium tuberculosis MmpL11 Cell Wall Lipid Transporter Is Important for Biofilm Formation, Intracellular Growth, and Nonreplicating Persistence.
Infection and immunity - 1 Aug 2017
Wright Catherine C, Hsu Fong Fu, Arnett Eusondia, Dunaj Jennifer L, Davidson Patrick M, Pacheco Sophia A, Harriff Melanie J, Lewinsohn David M, Schlesinger Larry S, Purdy Georgiana E
Abstract excerpt
The mycobacterial cell wall is crucial to the host-pathogen interface, because it provides a barrier against antibiotics and the host immune response. In addition, cell wall lipids are mycobacterial virulence factors. The mycobacterial membrane protein large (MmpL) proteins are cell wall lipid transporters that are important for basic mycobacterial physiology and Mycobacterium tuberculosis pathogenesis. MmpL3 and...
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