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Article

Gastric Cancer With Primitive Enterocyte Phenotype: An Aggressive Subgroup of Intestinal-type Adenocarcinoma.

The American journal of surgical pathology - 1 Jul 2017

Yamazawa Sho, Ushiku Tetsuo, Shinozaki-Ushiku Aya, Hayashi Akimasa, Iwasaki Akiko, Abe Hiroyuki, Tagashira Amane, Yamashita Hiroharu, Seto Yasuyuki, Aburatani Hiroyuki, Fukayama Masashi

Abstract excerpt

A primitive cell-like gene expression signature is associated with aggressive phenotypes of various cancers. We assessed the expression of phenotypic markers characterizing primitive cells and its correlation with clinicopathologic and molecular characteristics in gastric cancer. Immunohistochemical analysis of a panel of primitive phenotypic markers, including embryonic stem cell markers (OCT4, NANOG, SALL4,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28505005
DOI: 10.1097/PAS.0000000000000869

Genes

SALL4
CLDN6
GPC3
AFP
NANOG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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