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Article

Cardiomyocyte-specific loss of mitochondrial p32/C1qbp causes cardiomyopathy and activates stress responses.

Cardiovascular research - 1 Aug 2017

Saito Toshiro, Uchiumi Takeshi, Yagi Mikako, Amamoto Rie, Setoyama Daiki, Matsushima Yuichi, Kang Dongchon

Abstract excerpt

AIMS: Mitochondria are important organelles, dedicated to energy production. Mitochondrial p32/C1qbp, which functions as an RNA and protein chaperone, interacts with mitochondrial mRNA and is indispensable for mitochondrial function through its regulation of mitochondrial translation in cultured cell lines. However, the precise role of p32/C1qbp in vivo is poorly understood because of embryonic lethality in the...

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Source

Identifiers

PMID: 28498888
DOI: 10.1093/cvr/cvx095

Genes

FGF21

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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