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Article

FBXO32, encoding a member of the SCF complex, is mutated in dilated cardiomyopathy.

Genome biology - 11 Jan 2016

Al-Yacoub Nadya, Shaheen Ranad, Awad Salma Mahmoud, Kunhi Muhammad, Dzimiri Nduna, Nguyen Henry C, Xiong Yong, Al-Buraiki Jehad, Al-Habeeb Waleed, Alkuraya Fowzan S, Poizat Coralie

Abstract excerpt

BACKGROUND: Dilated cardiomyopathy (DCM) is a common form of cardiomyopathy causing systolic dysfunction and heart failure. Rare variants in more than 30 genes, mostly encoding sarcomeric proteins and proteins of the cytoskeleton, have been implicated in familial DCM to date. Yet, the majority of variants causing DCM remain to be identified. The goal of the study is to identify novel mutations causing familial...

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Source

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Identifiers

PMID: 26753747
DOI: 10.1186/s13059-015-0861-4
PMCID: PMC4707779

Genes

FBXO32

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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