Article
Sex Differences in Risk for Alzheimer's Disease Related to Neurotrophin Gene Polymorphisms: The Cache County Memory Study.
The journals of gerontology. Series A, Biological sciences and medical sciences - 9 Nov 2017
Matyi Joshua, Tschanz JoAnn T, Rattinger Gail B, Sanders Chelsea, Vernon Elizabeth K, Corcoran Chris, Kauwe John S K, Buhusi Mona
Abstract excerpt
Neurotrophins, including nerve-growth factor and brain-derived neurotrophic factor, have been implicated in Alzheimer's disease (AD). Associations between AD and neurotrophin signaling genes have been inconsistent, with few studies examining sex differences in risk. We examined four single-nucleotide polymorphisms (SNPs) involved in neurotrophin signaling (rs6265, rs56164415, rs2289656, rs2072446) and risk for AD...
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