Assessment of TREM2 rs75932628 association with Alzheimer's disease in a population-based sample: the Cache County Study.

doi:10.1016/j.neurobiolaging.2013.06.004

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Assessment of TREM2 rs75932628 association with Alzheimer's disease in a population-based sample: the Cache County Study.

Neurobiology of aging - 1 Dec 2013

Gonzalez Murcia Josue D, Schmutz Cameron, Munger Caitlin, Perkes Ammon, Gustin Aaron, Peterson Michael, Ebbert Mark T W, Norton Maria C, Tschanz Joann T, Munger Ronald G, Corcoran Christopher D, Kauwe John S K

Abstract excerpt

Recent studies have identified the rs75932628 (R47H) variant in TREM2 as an Alzheimer's disease risk factor with estimated odds ratio ranging from 2.9 to 5.1. The Cache County Memory Study is a large, population-based sample designed for the study of memory and aging. We genotyped R47H in 2974 samples (427 cases and 2540 control subjects) from the Cache County study using a custom TaqMan assay. We observed 7...

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PMID: 23855982
DOI: 10.1016/j.neurobiolaging.2013.06.004
PMCID: PMC3779500

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TREM2

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