Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Backup Mechanisms Maintain PACAP/VIP-Induced Arterial Relaxations in Pituitary Adenylate Cyclase-Activating Polypeptide-Deficient Mice.

Journal of vascular research - 1 Jan 2017

Ivic Ivan, Fulop Balazs D, Juhasz Tamas, Reglodi Dora, Toth Gabor, Hashimoto Hitoshi, Tamas Andrea, Koller Akos

Abstract excerpt

BACKGROUND: Pituitary adenylate cyclase-activating polypeptide (PACAP) is a multifunctional neuropeptide in the VIP/secretin/glucagon peptide superfamily. Two active forms, PACAP1-38 and PACAP1-27, act through G protein-coupled receptors, the PAC1 and VPAC1/2 receptors. Effects of PACAP include potent vasomotor activity. Vasomotor activity and organ-specific vasomotor effects of PACAP-deficient mice have not yet...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carotid Artery, Common
Share to Femoral Artery

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to In Vitro Techniques

Share to Peptide Fragments

Share to Pituitary Adenylate Cyclase-Activating Polypeptide

Share to Vasoactive Intestinal Peptide

Share to Vasodilation

Share to Vasodilator Agents

Source

Identifiers

PMID: 28490016
DOI: 10.1159/000457798

Genes

VIP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Backup Mechanisms Maintain PACAP/VIP-Induced Arterial Relaxations in Pituitary Adenylate Cyclase-Activating Polypeptide-Deficient Mice.PMID 28490016Read ↗

Aging-Induced Modulation of Pituitary Adenylate Cyclase-Activating Peptide- and Vasoactive Intestinal Peptide-Induced Vasomotor Responses in the Arteries of Mice.Semantic proximity Read ↗

New Insights into the Central PACAPergic System from the Phenotypes in PACAP‐ and PACAP Receptor‐Knockout MiceSemantic proximity Read ↗

Functional roles of the neuropeptide PACAP in brain and pancreas.Semantic proximity Read ↗

Mice deficient in both pituitary adenylyl cyclase-activating polypeptide and vasoactive intestinal peptide survive, but display growth retardation and sex-dependent early death.Semantic proximity Read ↗

Pituitary adenylate cyclase-activating polypeptides, PACAP-38 and PACAP-27, regulation of sympathetic neuron catecholamine, and neuropeptide Y expression through activation of type I PACAP/VIP receptor isoforms.Semantic proximity Read ↗

Recent advances in vasoactive intestinal peptide physiology and pathophysiology: focus on the gastrointestinal systemSemantic proximity Read ↗

Characterization of the PAC1 variants expressed in the mouse heart.Semantic proximity Read ↗

[Altered higher brain function in PACAP-knockout mice].Semantic proximity Read ↗

Constitutive and conditional deletion reveals distinct phenotypes driven by developmental versus neurotransmitter actions of the neuropeptide PACAP.Semantic proximity Read ↗

Noncompensation in peptide/receptor gene expression and distinct behavioral phenotypes in VIP- and PACAP-deficient mice.Semantic proximity Read ↗

The alpha2-isoform of Na-K-ATPase mediates ouabain-induced hypertension in mice and increased vascular contractility in vitro.Semantic proximity Read ↗

Calcitonin Gene-Related Peptide Protects Against Cardiovascular Dysfunction Independently of Nitric Oxide In VivoSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.