Article
Characterization of the PAC1 variants expressed in the mouse heart.
Annals of the New York Academy of Sciences - 1 Jul 2006
Ushiyama Mina, Sugawara Hideki, Inoue Kazuhiko, Kangawa Kenji, Yamada Katsushi, Miyata Atsuro
Abstract excerpt
Pituitary adenylate cyclase-activating polypeptide (PACAP), a pleiotropic neuropeptide, exerts a variety of physiological functions through three types of G protein-coupled receptors, PAC1, VPAC1, and VAPC2. Characterization of the molecular forms of PAC1 in mouse heart revealed the presence of four types of variant receptors harboring the N or S variant in the first extracellular domain (EC1 domain) with or...
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