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Cryptococcus neoformans Host Adaptation: Toward Biological Evidence of Dormancy

1 Apr 2015

Abstract excerpt

UNLABELLED: Cryptococcosis is an opportunistic infection due to the ubiquitous yeast Cryptococcus neoformans. This yeast interacts closely with innate immune cells, leading to various fates, including fungal persistence within cells, making possible the dissemination of the yeast cells with monocytes via a Trojan horse strategy. In humans, the natural history of the infection begins with primoinfection during...

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PMID: 25827423
DOI: 10.1128/mbio.02580-14

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