Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of putative regulatory single-nucleotide variants in NTN1 gene associated with NSCL/P.

Journal of human genetics - 1 Jul 2023

Tao Hong-Xu, Yang Yi-Xin, Shi Bing, Jia Zhong-Lin

Abstract excerpt

Non-syndromic cleft lip with or without cleft palate (NSCL/P) is a common polygenetic disease. Although genome-wide association studies (GWAS) identified NTN1 gene as a high-priority candidate of NSCL/P, the comprehensive genetic architecture of NTN1 weren't yet known. Thus, this study aimed to determine full-scale genetic variants of NTN1 for NSCL/P in Chinese Han people. Initially, targeted sequencing of NTN1...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Cleft Lip
Share to Cleft Palate

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Genome-Wide Association Study

Share to Netrin-1

Share to Nucleotides

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 36879001
DOI: 10.1038/s10038-023-01137-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of putative regulatory single-nucleotide variants in NTN1 gene associated with NSCL/P.PMID 36879001Read ↗

The functional variant of NTN1 contributes to the risk of nonsyndromic cleft lip with or without cleft palate.Semantic proximity Read ↗

Identification of susceptibility genes in non-syndromic cleft lip with or without cleft palate using whole-exome sequencing.Semantic proximity Read ↗

[Research progress in regulatory variants in non-coding regions in non-syndromic cleft lip with or without cleft palate].Semantic proximity Read ↗

Homozygote C/C at rs12543318 was risk factor for non-syndromic cleft lip only from Western Han Chinese population.Semantic proximity Read ↗

Identification of Novel Genomic Variations in Susceptibility to Nonsyndromic Cleft Lip and Palate PatientsSemantic proximity Read ↗

Rs9891446 in NTN1 is associated with right-side cleft lip in Han Chinese population.Semantic proximity Read ↗

[Genetic and functional research strategies of non-syndromic cleft lip with or without cleft palate in the post genome-wide association study era].Semantic proximity Read ↗

[Exploring the association between de novo mutations and non-syndromic cleft lip with or without palate based on whole exome sequencing of case-parent trios].Semantic proximity Read ↗

Exploration of Genetic Variants of Non-syndromic Cleft Lip with or without Palate and Underlying Mechanisms.Semantic proximity Read ↗

[Progress in next-generation sequencing research of non-syndromic oral clefts].Semantic proximity Read ↗

[Single nucleotide polymorphism heritability of non-syndromic cleft lip with or without cleft palate in Chinese population].Semantic proximity Read ↗

Association Between SNPs in 1q32.2 and NSCL ± P in Han Chinese Population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.