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Article

The Zebrafish curly fry Is Required for Proper Centrosome and Mitotic Spindle Assembly.

Zebrafish - 1 Aug 2017

Song Mi Hye, Medley Jeffrey C, Kuwada John Y

Abstract excerpt

The zebrafish curly fry (cfy) mutation leads to a dramatic increase in mitotic index and cell death starting during neural tube formation. The mutant phenotype is cell autonomous and does not result from defects in apical/basal polarity within the neuroepithelium. The increase in mitotic index could be due to increased proliferation or cell cycle arrest in mitosis. cfy embryos were analyzed to examine these two...

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Share to Cell Cycle Checkpoints
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28488934
DOI: 10.1089/zeb.2017.1427
PMCID: PMC5549795

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