Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Recombinant TgHSP70 Immunization Protects against Toxoplasma gondii Brain Cyst Formation by Enhancing Inducible Nitric Oxide Expression.

Frontiers in cellular and infection microbiology - 1 Jan 2017

Czarnewski Paulo, Araújo Ester C B, Oliveira Mário C, Mineo Tiago W P, Silva Neide M

Abstract excerpt

Toxoplasma gondii is known to cause congenital infection in humans and animals and severe disease in immunocompromised individuals; consequently development of vaccines against the parasite is highly necessary. Under stress conditions, T. gondii expresses the highly immunogenic heat shock protein 70 (TgHSP70). Here, we assessed the protective efficacy of rTgHSP70 immunization combined with Alum in oral ME-49 T....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adjuvants, Immunologic
Share to Antibodies, Protozoan

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Nitric Oxide Synthase Type II

Share to RAW 264.7 Cells

Share to Toxoplasma

Share to Toxoplasmosis

Share to Vaccines, Synthetic

Source

Open in PubMed Open full text

Identifiers

PMID: 28487847
DOI: 10.3389/fcimb.2017.00142
PMCID: PMC5403831

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Recombinant TgHSP70 Immunization Protects against Toxoplasma gondii Brain Cyst Formation by Enhancing Inducible Nitric Oxide Expression.PMID 28487847Read ↗

Immunization With a DNA Vaccine Cocktail Encoding TgPF, TgROP16, TgROP18, TgMIC6, and TgCDPK3 Genes Protects Mice Against Chronic ToxoplasmosisSemantic proximity Read ↗

Protective Efficacy of a Toxoplasma gondii Rhoptry Protein 13 Plasmid DNA Vaccine in MiceSemantic proximity Read ↗

ROLES OF IFN-γ ON STAGE CONVERSION OF AN OBLIGATE INTRACELLULAR PROTOZOAN PARASITE, Toxoplasma GondiiSemantic proximity Read ↗

Intranasal immunization with SAG1 and nontoxic mutant heat-labile enterotoxins protects mice against Toxoplasma gondii.Semantic proximity Read ↗

Evaluation of immune protection againstToxoplasma gondiiinfection in mice induced by a multi-antigenic DNA vaccine containing TgGRA24, TgGRA25 and TgMIC6Semantic proximity Read ↗

Vaccines against Toxoplasma gondii: challenges and opportunities.Semantic proximity Read ↗

Evaluation of Toxoplasma gondii as a live vaccine vector in susceptible and resistant hostsSemantic proximity Read ↗

The Immunogenic and Immunoprotective Activities of Recombinant Chimeric T. gondii Proteins Containing AMA1 Antigen FragmentsSemantic proximity Read ↗

Induction of Protective Immune Responses by a Multiantigenic DNA Vaccine Encoding GRA7 and ROP1 of Toxoplasma gondiiSemantic proximity Read ↗

Toxoplasma gondii induces robust humoral immune response against cyst wall antigens in chronically infected animals and humansSemantic proximity Read ↗

Inhibition of inducible nitric oxide synthase exacerbates chronic cerebral toxoplasmosis in Toxoplasma gondii-susceptible C57BL/6 mice but does not reactivate the latent disease in T. gondii-resistant BALB/c mice.Semantic proximity Read ↗

Toxoplasma gondii induction of interleukin-12 is associated with acute virulence in mice and depends on the host genotype.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.