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Evaluation of Toxoplasma gondii as a live vaccine vector in susceptible and resistant hosts

28 Aug 2011

Abstract excerpt

BACKGROUND: Toxoplasma gondii has been shown to trigger strong cellular immune responses to heterologous antigens expressed by the parasite in the inbred mouse model. We studied the immune response induced by T. gondii as an effective vaccine vector in chickens and rabbits. RESULTS: T. gondii RH strain was engineered to express the yellow fluorescent protein (YFP) in the cytoplasm. A subcutaneous injection of the...

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PMID: 21871123
DOI: 10.1186/1756-3305-4-168

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