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Article

Sequencing of cancer cell subpopulations identifies micrometastases in a bladder cancer patient.

Oncotarget - 11 Jul 2017

Prado Kris, Zhang Kelvin X, Pellegrini Matteo, Chin Arnold I

Abstract excerpt

PURPOSE: Pathologic staging of bladder cancer patients remains a challenge. Standard-of-care histology exhibits limited sensitivity in detection of micrometastases, which can increase risk of cancer progression and delay potential adjuvant therapies. Here, we sought to develop a proof of concept novel molecular approach to improve detection of cancer micrometastasis. EXPERIMENTAL DESIGN: We combined fluorescence...

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Identifiers

PMID: 28487492
DOI: 10.18632/oncotarget.17312
PMCID: PMC5542213

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