Article
HMEC-1 adopt the mixed amoeboid-mesenchymal migration type during EndMT.
European journal of cell biology - 1 Jun 2017
Kryczka Jakub, Przygodzka Patrycja, Bogusz Helena, Boncela Joanna
Abstract excerpt
The contribution of endothelial cells to scar and fibrotic tissue formation is undisputedly connected to their ability to undergo the endothelial-to-mesenchymal transition (EndMT) towards fibroblast phenotype-resembling cells. The migration model of fibroblasts and fibroblast-resembling cells is still not fully understood. It may be either a Rho/ROCK-independent, an integrin- and MMP-correlated ECM...
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